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首页  >  重组蛋白  >  Human ABCB11 Recombinant Protein
ABCB11 (基因名), Bile salt export pump (蛋白名), ABCBB_HUMAN.
产品名称:

Human ABCB11/ Bile salt export pump Recombinant Protein
胆盐出口泵

货号:

R10415h

商标:
EIAab®
监管等级:
别名:

ATP-binding cassette sub-family B member 11, BSEP

序列号:
O95342
来源:
E.coli
种属:
Human
标签:
His
序列:
523-729aa
预估分子量:
22.77 kDa (monomer)
纯度:
Greater than 90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cardiovascular
Human ABCB11 Protein
规格 & 价格: cart
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产品说明书
说明书: 下载说明书
MSDS: MSDS


R&D 技术数据
Human ABCB11 Protein
Recombinant human ABCB11 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 2q31.1 by HGNC 2q31.1 by Entrez Gene 2q31.1 by Ensembl
ABCB11 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with HAX1.


功能:
Involved in the ATP-dependent secretion of bile salts into the canaliculus of hepatocytes.


亚细胞位置:
Membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Mutations and polymorphisms in the bile salt export pump and the multidrug resistance protein 3 associated with drug-induced liver injury."

[2].
"Sequence analysis of bile salt export pump (ABCB11) and multidrug resistance p-glycoprotein 3 (ABCB4, MDR3) in patients with intrahepatic cholestasis of pregnancy."

[3].
"A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis."

[4].
"Polymorphic variants in the human bile salt export pump (BSEP; ABCB11): functional characterization and interindividual variability."

[5].
"Common variants of ABCB4 and ABCB11 and plasma lipid levels: a study in sib pairs with gallstones, and controls."

[6].
"Genetic variability, haplotype structures, and ethnic diversity of hepatic transporters MDR3 (ABCB4) and bile salt export pump (ABCB11)."

[7].
"Impaired expression and function of the bile salt export pump due to three novel ABCB11 mutations in intrahepatic cholestasis."

[8].
"BSEP and MDR3 haplotype structure in healthy Caucasians, primary biliary cirrhosis and primary sclerosing cholangitis."

[9].
"FIC1 and BSEP defects in Taiwanese patients with chronic intrahepatic cholestasis with low gamma-glutamyltranspeptidase levels."

[10].
"Diagnosis of ABCB11 gene mutations in children with intrahepatic cholestasis using high resolution melting analysis and direct sequencing."
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