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首页  >  重组蛋白  >  Human ABCB5 Recombinant Protein
ABCB5 (基因名), ATP-binding cassette sub-family B member 5 (蛋白名), ABCB5_HUMAN.
产品名称:

Human ABCB5/ ATP-binding cassette sub-family B member 5 Recombinant Protein
atp结合盒亚家族B成员5

货号:

R10410h

商标:
EIAab®
监管等级:
别名:

ABCB5 P-gp, P-glycoprotein ABCB5

序列号:
Q2M3G0
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human ABCB5 Protein
规格 & 价格: cart
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Human ABCB5 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 7p21.1 by HGNC 7p21.1 by Entrez Gene 7p21.1 by Ensembl
ABCB5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Drug efflux transporter present in a number of stem cells that acts as a regulator of cellular differentiation. Able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair.


亚细胞位置:
Cell membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Regulation of progenitor cell fusion by ABCB5 P-glycoprotein, a novel human ATP-binding cassette transporter."

[2].
"ABCB5 maintains melanoma-initiating cells through a proinflammatory cytokine signaling circuit."

[3].
"ABCB5 is a limbal stem cell gene required for corneal development and repair."

[4].
"Genetically determined ABCB5 functionality correlates with pigmentation phenotype and melanoma risk."

[5].
"Expression of ABCB5 gene in hematological malignances and its significance."
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