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Abca4 (基因名), Retinal-specific phospholipid-transporting ATPase ABCA4 (蛋白名), ABCA4_MOUSE.
产品名称:

Mouse Abca4/ Retinal-specific phospholipid-transporting ATPase ABCA4 Recombinant Protein
视网膜特异性磷脂转运atp酶ABCA4

货号:

R10399m

商标:
EIAab®
监管等级:
别名:

ATP-binding cassette sub-family A member 4, RIM ABC transporter, Retinal-specific ATP-binding cassette transporter, RIM protein, Abcr

序列号:
O35600
来源:
E.coli
种属:
Mouse
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Mouse Abca4 Protein
规格 & 价格: cart
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Mouse Abca4 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
N/A


功能:
Catalyzes the translocation of specific phospholipids from the extracellular/lumenal to the cytoplasmic leaflet of membrane coupled to the hydrolysis of ATP. Transports preferentially phosphatidylethanolamine. In the visual cycle, acts as an inward-directed retinoid flipase, retinoid substrates imported by ABCA4 from the extracellular or intradiscal (rod) membrane surfaces to the cytoplasmic membrane surface are all-trans-retinaldehyde (ATR) and N-retinyl-phosphatidyl-ethanolamine (NR-PE). Once transported to the cytoplasmic surface, ATR is reduced to vitamin A by trans-retinol dehydrogenase (tRDH) and then transferred to the retinal pigment epithelium (RPE) where it is converted to 11-cis-retinal. May play a role in photoresponse, removing ATR/NR-PE from the extracellular photoreceptor surfaces during bleach recovery.


亚细胞位置:
Membrane Multi-pass membrane protein Endoplasmic reticulum Localized to outer segment disk edges of rods and cones, with around one million copies/photoreceptor.


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