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首页  >  重组蛋白  >  Human APBB1IP Recombinant Protein
APBB1IP (基因名), Amyloid beta A4 precursor protein-binding family B member 1-interacting protein (蛋白名), AB1IP_HUMAN.
产品名称:

Human APBB1IP/ Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

APBB1-interacting protein 1, Proline-rich EVH1 ligand 1, Proline-rich protein 73, Rap1-GTP-interacting adapter molecule, Retinoic acid-responsive proline-rich protein 1, PREL-1, RIAM, RARP-1, PREL1, RARP1, RIAM

序列号:
Q7Z5R6
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human APBB1IP Protein
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Human APBB1IP Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


基因位点
Cytogenetic band: 10p12.1 by HGNC 10p12.1 by Entrez Gene 10p12.1 by Ensembl
APBB1IP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts, through the N-terminal Pro-rich region, with the WW domain of APBB1. Interacts with RAP1A, PFN1, TLN1, VASP, VCL and ENAH.


功能:
Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion.


亚细胞位置:
Cell membrane Peripheral membrane protein Cell projection Lamellipodium Cell junction Focal adhesion Cytoplasm Cytoskeleton Colocalizes with ENA/VASP proteins at lamellipodia tips and focal adhesions, and F-actin at the leading edge. At the membrane surface, associates, via the PH domain, preferentially with the inositol phosphates, PtdIns(5)P and PtdIns(3)P. This binding appears to be necessary for the efficient interaction of the RA domain to Ras-GTPases (By similarity).


该产品尚未在任何出版物中被引用。

[1].
"RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion."

[2].
"The retinoic acid-responsive proline-rich protein is identified in promyeloleukemic HL-60 cells."

[3].
"A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network."

[4].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."

[5].
"Association studies of 23 positional/functional candidate genes on chromosome 10 in late-onset Alzheimer's disease."

[6].
"A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease."

[7].
"PREL1 provides a link from Ras signalling to the actin cytoskeleton via Ena/VASP proteins."

[8].
"The DNA sequence and comparative analysis of human chromosome 10."

[9].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[10].
"The WW domain of neural protein FE65 interacts with proline-rich motifs in Mena, the mammalian homolog of Drosophila enabled."
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