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AADAT (基因名), Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (蛋白名), AADAT_HUMAN.
产品名称:

Human AADAT/ Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Recombinant Protein
犬尿氨酸/线粒体氨基已二酸转氨酶α

货号:

R12537h

商标:
EIAab®
监管等级:
别名:

2-aminoadipate aminotransferase, 2-aminoadipate transaminase, Alpha-aminoadipate aminotransferase, Kynurenine aminotransferase II, Kynurenine--oxoglutarate aminotransferase II, Kynurenine--oxoglutarate transaminase 2, Kynurenine--oxoglutarate transaminase II, AadAT, KAT/AadAT, KAT2

序列号:
Q8N5Z0
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cell Biology
Human AADAT Protein
规格 & 价格: cart
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Human AADAT Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 4q33 by HGNC 4q33 by Entrez Gene 4q33 by Ensembl
AADAT Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer.


功能:
Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro).


亚细胞位置:
Mitochondrion


该产品尚未在任何出版物中被引用。

[1].
"Crystal structure of human kynurenine aminotransferase II."

[2].
"Crystal structure of human kynurenine aminotransferase II, a drug target for the treatment of schizophrenia."

[3].
"Substrate specificity and structure of human aminoadipate aminotransferase/kynurenine aminotransferase II."

[4].
"Characterization of the human gene encoding alpha-aminoadipate aminotransferase (AADAT)."

[5].
"Genomic organization and expression analysis of mouse kynurenine aminotransferase II, a possible factor in the pathophysiology of Huntington's disease."

[6].
"Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression."

[7].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[8].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[9].
"2-Aminoadipate-2-oxoglutarate aminotransferase isoenzymes in human liver: a plausible physiological role in lysine and tryptophan metabolism."

[10].
"Architecture of the human interactome defines protein communities and disease networks."
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