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Atxn7l3b (基因名), Ataxin-7-like protein 3B (蛋白名), A7L3B_MOUSE.
产品名称:

Mouse Atxn7l3b/ Ataxin-7-like protein 3B Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
序列号:
Q3UD01
来源:
E.coli
种属:
Mouse
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Mouse Atxn7l3b Protein
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Mouse Atxn7l3b Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Interacts strongly with ENY2. Interacts weakly with USP22.


功能:
By binding to ENY2, interferes with the nuclear functions of the deubiquitinase (DUB) module of the SAGA complex which consists of ENY2, ATXN7, ATXN7L3 and the histone deubiquitinating component USP22. Affects USP22 DUB activity toward histones indirectly by changing the subcellular distribution of ENY2 and altering ENY2 availability for ATXN7L3 interaction. Regulates H2B monoubiquitination (H2Bub1) levels through cytoplasmic sequestration of ENY2 resulting in loss of nuclear ENY2-ATXN7L3 association which destabilizes ATXN7L3. Affects protein expression levels of ENY2 and ATXN7L3.


亚细胞位置:
Cytoplasm


该产品尚未在任何出版物中被引用。
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