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A4GALT (基因名), Lactosylceramide 4-alpha-galactosyltransferase (蛋白名), A4GAT_HUMAN.
产品名称:

Human A4GALT/ Lactosylceramide 4-alpha-galactosyltransferase Recombinant Protein

货号:

R16260h

商标:
EIAab®
监管等级:
别名:

Alpha-1, 4-N-acetylglucosaminyltransferase, Alpha-1, 4-galactosyltransferase, Alpha4Gal-T1, CD77 synthase, Globotriaosylceramide synthase, P1/Pk synthase, UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase, Gb3 synthase, A14GALT, A4GALT1

序列号:
Q9NPC4
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human A4GALT Protein
规格 & 价格: cart
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Human A4GALT Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 22q13.2 by HGNC 22q13.2 by Entrez Gene 22q13.2 by Ensembl
A4GALT Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins.


亚细胞位置:
Golgi apparatus membrane Single-pass type II membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Three-base deletion and one-base insertion of the alpha(1,4)galactosyltransferase gene responsible for the P phenotype."

[2].
"Cloning of Gb3 synthase, the key enzyme in globo-series glycosphingolipid synthesis, predicts a family of alpha 1, 4-glycosyltransferases conserved in plants, insects, and mammals."

[3].
"Cloning and expression of the histo-blood group Pk UDP-galactose: Ga1beta-4G1cbeta1-cer alpha1, 4-galactosyltransferase. Molecular genetic basis of the p phenotype."

[4].
"Molecular basis for the p phenotype. Identification of distinct and multiple mutations in the alpha 1,4-galactosyltransferase gene in Swedish and Japanese individuals."

[5].
"A single point mutation in the gene encoding Gb3/CD77 synthase causes a rare inherited polyagglutination syndrome."

[6].
"Identification of a novel A4GALT exon reveals the genetic basis of the P1/P2 histo-blood groups."

[7].
"Globotriaosylceramide (Gb3) content in HeLa cells is correlated to Shiga toxin-induced cytotoxicity and Gb3 synthase expression."

[8].
"Expression of a novel missense mutation found in the A4GALT gene of Amish individuals with the p phenotype."

[9].
"Two previously proposed P1/P2-differentiating and nine novel polymorphisms at the A4GALT (Pk) locus do not correlate with the presence of the P1 blood group antigen."

[10].
"Genetic heterogeneity at the glycosyltransferase loci underlying the GLOB blood group system and collection."
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