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SERPINA1 (基因名), Alpha-1-antitrypsin (蛋白名), A1AT_HUMAN.
产品名称:

Human SERPINA1/ Alpha-1-antitrypsin Recombinant Protein
Alpha-1-antiproteinase

货号:

R1697h

商标:
EIAab®
监管等级:
别名:

Alpha-1 protease inhibitor, Alpha-1-antiproteinase, Serpin A1, PRO0684, PRO2209, AAT, PI

序列号:
P01009
来源:
E.coli
种属:
Human
标签:
His
序列:
25-418aa
预估分子量:
43.34 kDa (monomer)
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human SERPINA1 Protein
规格 & 价格: cart
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 14q32.13 by HGNC 14q32.13 by Entrez Gene 14q32.13 by Ensembl
SERPINA1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
The variants S and Z interact with CANX AND PDIA3.


功能:
Short peptide from AAT: reversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. Its major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE).


亚细胞位置:
Short peptide from AAT Secreted Extracellular space Extracellular matrix


该产品尚未在任何出版物中被引用。

[1].
"Polymorphisms in the SERPINA1 (Alpha-1-Antitrypsin) gene are associated with severe chronic rhinosinusitis unresponsive to medical therapy."

[2].
"Prevalence of genetic polymorphisms in the promoter region of the alpha-1 antitrypsin (SERPINA1) gene in chronic liver disease: a case control study."

[3].
"Alpha-1-antitrypsin phenotypes in adult liver disease patients."

[4].
"Real time PCR detection of the PI*Z and PI*S mutations associated with alpha-1 antitrypsin deficiency."

[5].
"Prevalence of common HFE and SERPINA1 mutations in patients with hepatocellular carcinoma in a Moroccan population."

[6].
"SERPINA1 gene variants in individuals from the general population with reduced alpha1-antitrypsin concentrations."

[7].
"Isoelectric focusing phenotyping and denaturing gradient gel electrophoresis genotyping: a comparison of two methods in detection of alpha-1-antitrypsin variants."

[8].
"Determination of alpha 1-antitrypsin levels and of the presence of S and Z alleles in a population of patients with chronic respiratory symptoms."

[9].
"An alpha-1 antitrypsin genetic variant from India."

[10].
"Haplotypes of the alpha-1 antitrypsin gene in healthy controls and Z deficiency patients."
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