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ORM1 (基因名), Alpha-1-acid glycoprotein 1 (蛋白名), A1AG1_HUMAN.
产品名称:

Human ORM1/ Alpha-1-acid glycoprotein 1 Recombinant Protein
α1酸性糖蛋白1

货号:

R0816h

商标:
EIAab®
监管等级:
别名:

Orosomucoid-1, OMD 1, AGP 1, AGP1

序列号:
P02763
来源:
E.coli
种属:
Human
标签:
His
序列:
19-201aa
预估分子量:
20.13 kDa (monomer)
纯度:
Greater than 95% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Immunology
  • Human ORM1 Protein
  • Human ORM1 Protein
  • Human ORM1 Protein
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Human ORM1 Protein
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
The sequence analysis of human ORM1 protein including hydrophilcity, hydrophobicity and antigenicity.
Human ORM1 Protein
Recombinant human ORM1 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 9q32 by HGNC 9q32 by Entrez Gene 9q32 by Ensembl
ORM1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction.


亚细胞位置:
Secreted



[1].
"Orosomucoid influences the response to antidepressants in major depressive disorder."

[2].
"Human orosomucoid polymorphism: molecular basis of the three common ORM1 alleles, ORM1*F1, ORM1*F2, and ORM1*S."

[3].
"Genetic factors (VKORC1, CYP2C9, EPHX1, and CYP4F2) are predictor variables for warfarin response in very elderly, frail inpatients."

[4].
"The IFNG (IFN-gamma) genotype predicts cytogenetic and molecular response to imatinib therapy in chronic myeloid leukemia."

[5].
"Investigation of genetic variants of alpha-1 acid glycoprotein by ultra-performance liquid chromatography-mass spectrometry."

[6].
"Genetic variants in the candidate genes of the apoptosis pathway and susceptibility to chronic myeloid leukemia."

[7].
"Genetic determinants of warfarin dosing in the Han-Chinese population."

[8].
"Genetic factors contribute to patient-specific warfarin dose for Han Chinese."

[9].
"Population pharmacokinetics and pharmacogenetics of imatinib in children and adults."

[10].
"The 1.8-A crystal structure of alpha1-acid glycoprotein (Orosomucoid) solved by UV RIP reveals the broad drug-binding activity of this human plasma lipocalin."
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