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HTR6 (基因名), 5-hydroxytryptamine receptor 6 (蛋白名), 5HT6R_HUMAN.
产品名称:

Human HTR6/ 5-hydroxytryptamine receptor 6 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Serotonin receptor 6, 5-HT-6

序列号:
P50406
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human HTR6 Protein
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Human HTR6 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


基因位点
Cytogenetic band: 1p36.13 by HGNC 1p36.13 by Entrez Gene 1p36.13 by Ensembl
HTR6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with MTOR, RPTOR and NF1 (PubMed:23027611). Interacts with CDK5.


功能:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs (By similarity). Controls pyramidal neurons migration during corticogenesis, through the regulation of CDK5 activity (By similarity). Is an activator of TOR signaling (PubMed:23027611).


亚细胞位置:
Cell membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Risperidone-related weight gain: genetic and nongenetic predictors."

[2].
"No association of 5-HT2C, 5-HT6, and tryptophan hydroxylase-1 gene polymorphisms with personality traits in the Japanese population."

[3].
"Serotonergic genes and personality traits in the Korean population."

[4].
"Risperidone response and 5-HT6 receptor gene variance: genetic association analysis with adjustment for nongenetic confounders."

[5].
"Association of the HTR6 polymorphism C267T with late-onset Alzheimer's disease in Chinese."

[6].
"5-Hydroxytryptamine 6 receptor (5-HT(6)) receptor and apolipoprotein E (ApoE) polymorphisms in patients with Alzheimer's disease in the Basque Country."

[7].
"[Associations between six functional genes and schizophrenia]."

[8].
"Lack of association between the T-->C 267 serotonin 5-HT6 receptor gene (HTR6) polymorphism and prediction of response to clozapine in schizophrenia."

[9].
"Serotonin 6 receptor polymorphism in schizophrenia: frequency, age at onset and cognitive function."

[10].
"Association analysis of HTR6 and HTR2A polymorphisms in sporadic Alzheimer's disease."
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