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首页  >  重组蛋白  >  Mouse Htr2a Recombinant Protein
Htr2a (基因名), 5-hydroxytryptamine receptor 2A (蛋白名), 5HT2A_MOUSE.
产品名称:

Mouse Htr2a/ 5-hydroxytryptamine receptor 2A Recombinant Protein
5-羟色胺受体2

货号:

R10283m

商标:
EIAab®
监管等级:
别名:

Serotonin receptor 2A, 5-HT-2, Htr2

序列号:
P35363
来源:
E.coli
种属:
Mouse
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Mouse Htr2a Protein
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Mouse Htr2a Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Interacts with MPDZ and PATJ. May interact with MPP3, PRDX6, DLG4, DLG1, CASK, APBA1 and MAGI2 (By similarity). Interacts with GRM2 and DRD2; this may affect signaling.


功能:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores. Affects neural activity, perception, cognition and mood. Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction.


亚细胞位置:
Cell membrane Multi-pass membrane protein Cell projection Dendrite Cell projection Axon Cytoplasmic vesicle Membrane Caveola Localizes to the postsynaptic thickening of axo-dendritic synapses.


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