Htr1d (GeneName), 5-hydroxytryptamine receptor 1D (ProteinName), 5HT1D_MOUSE.
Mouse Htr1d/ 5-hydroxytryptamine receptor 1D Recombinant Protein
5-HT-1D,Serotonin receptor 1D,Gpcr14
>90% by SDS-PAGE
Please contact the technician for more information.
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
Store at -20°C. (Avoid repeated freezing and thawing.)
Homodimer. Heterodimer with HTR1B.
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity. May also play a role in regulating the release of other neurotransmitters. May play a role in vasoconstriction.
Cell membrane Multi-pass membrane protein
MSPPNQSLEG | LPQEASNRSL | NVTGAWDPEV | LQALRISLVV | VLSVITLATV |
LSNAFVLTTI | LLTKKLHTPA | NYLIGSLATT | DLLVSILVMP | ISIAYTTTRT |
WNFGQILCDI | WVSSDITCCT | ASILHLCVIA | LDRYWAITDA | LEYSKRRTAG |
HAAAMIAAVW | IISICISIPP | LFWRQATAHE | EMSDCLVNTS | QISYTIYSTC |
GAFYIPSILL | IILYGRIYVA | ARSRILNPPS | LYGKRFTTAQ | LITGSAGSSL |
CSLNPSLHES | HTHTVGSPLF | FNQVKIKLAD | SILERKRISA | ARERKATKTL |
GIILGAFIIC | WLPFFVVSLV | LPICRDSCWI | HPALFDFFTW | LGYLNSLINP |
VIYTVFNEDF | RQAFQKVVHF | RKIS
This product has not yet been referenced specifically in any publications.
"The serotonin 5-HT1D receptor gene and attention-deficit hyperactivity disorder in Chinese Han subjects."
"Human serotonin 1D receptor is encoded by a subfamily of two distinct genes: 5-HT1D alpha and 5-HT1D beta."
"Association study of the serotoninergic system in migraine in the Spanish population."
"Genetic susceptibility to distinct bladder cancer subphenotypes."
"Association study of 182 candidate genes in anorexia nervosa."
"Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?"
"Hundreds of variants clustered in genomic loci and biological pathways affect human height."
"Serotonin genes and gene-gene interactions in borderline personality disorder in a matched case-control study."
"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."
"Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis."
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