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Home  >  Protein  >  Human HTR1D Recombinant Protein
HTR1D (GeneName), 5-hydroxytryptamine receptor 1D (ProteinName), 5HT1D_HUMAN.
Product Name:

Human HTR1D/ 5-hydroxytryptamine receptor 1D Recombinant Protein

 
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

5-HT-1D,Serotonin 1D alpha receptor,5-HT-1D-alpha,Serotonin receptor 1D,HTR1DA,HTRL

Source:
E.coli
Species:
Human
Tags:
His
Purity:
>90% by SDS-PAGE
Concentration:
Reconstitution Dependent
Form:
Liquid
Endotoxin Level:
Please contact the technician for more information.
Storage Buffer:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
Storage:
Store at -20°C. (Avoid repeated freezing and thawing.)
Research Area:
-
Human HTR1D Protein
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Human HTR1D Protein
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Product Datasheets
Instruction:
MSDS:


Genomic View
Cytogenetic band: 1p36.12 by HGNC 1p36.12 by Entrez Gene 1p36.12 by Ensembl
HTR1D Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
General Annotation


Sub Unit:
Homodimer. Heterodimer with HTR1B.


Function:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity. May also play a role in regulating the release of other neurotransmitters. May play a role in vasoconstriction.


Subcellular Location:
Cell membrane Multi-pass membrane protein


This product has not yet been referenced specifically in any publications.

[1].
"The serotonin 5-HT1D receptor gene and attention-deficit hyperactivity disorder in Chinese Han subjects."

[2].
"Human serotonin 1D receptor is encoded by a subfamily of two distinct genes: 5-HT1D alpha and 5-HT1D beta."

[3].
"Association study of the serotoninergic system in migraine in the Spanish population."

[4].
"Genetic susceptibility to distinct bladder cancer subphenotypes."

[5].
"Association study of 182 candidate genes in anorexia nervosa."

[6].
"Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?"

[7].
"Hundreds of variants clustered in genomic loci and biological pathways affect human height."

[8].
"Serotonin genes and gene-gene interactions in borderline personality disorder in a matched case-control study."

[9].
"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."

[10].
"Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis."
Sample Data
Sample Data
Sample Data
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