HTR1B (GeneName), 5-hydroxytryptamine receptor 1B (ProteinName), 5HT1B_HUMAN.
Human HTR1B/ 5-hydroxytryptamine receptor 1B Recombinant Protein
5-HT-1B,S12,Serotonin 1D beta receptor,5-HT-1D-beta,Serotonin receptor 1B,HTR1DB
Predicted Molecular Mass:
33.77 kDa (monomer)
Greater than 92% by SDS-PAGE
Please contact the technician for more information.
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
Store at -20°C. (Avoid repeated freezing and thawing.)
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: firstname.lastname@example.org.
Homodimer. Heterodimer with HTR1D.
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances, such as lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries.
Cell membrane Multi-pass membrane protein
MEEPGAQCAP | PPPAGSETWV | PQANLSSAPS | QNCSAKDYIY | QDSISLPWKV |
LLVMLLALIT | LATTLSNAFV | IATVYRTRKL | HTPANYLIAS | LAVTDLLVSI |
LVMPISTMYT | VTGRWTLGQV | VCDFWLSSDI | TCCTASILHL | CVIALDRYWA |
ITDAVEYSAK | RTPKRAAVMI | ALVWVFSISI | SLPPFFWRQA | KAEEEVSECV |
VNTDHILYTV | YSTVGAFYFP | TLLLIALYGR | IYVEARSRIL | KQTPNRTGKR |
LTRAQLITDS | PGSTSSVTSI | NSRVPDVPSE | SGSPVYVNQV | KVRVSDALLE |
KKKLMAARER | KATKTLGIIL | GAFIVCWLPF | FIISLVMPIC | KDACWFHLAI |
FDFFTWLGYL | NSLINPIIYT | MSNEDFKQAF | HKLIRFKCTS |
This product has not yet been referenced specifically in any publications.
"Lack of association between five serotonin metabolism-related genes and medication overuse headache."
"[Association study of HTR1A and HTR1B with adolescent idiopathic scoliosis]."
"Comorbidity between bipolar disorder and alcohol use disorder: association of dopamine and serotonin gene polymorphisms."
"Fluoxetine response in impulsive-aggressive behavior and serotonin transporter polymorphism in personality disorder."
"Functional polymorphisms in the serotonin 1B receptor gene (HTR1B) predict self-reported anger and hostility among young men."
"SSRI response in depression may be influenced by SNPs in HTR1B and HTR1A."
"An association study of the serotonin transporter and receptor genes with the suicidal ideation of major depression in a Chinese Han population."
"Association analysis of serotonin receptor 1B (HTR1B) and brain-derived neurotrophic factor gene polymorphisms in Borderline personality disorder."
"The relationship between serotonin receptor 1B polymorphisms A-161T and alcohol dependence."
"HTR1B and HTR2C in autism spectrum disorders in Brazilian families."
Displaying results : 0
No feedback yet, let's comment.
Product Name *
Size Quantity Price ($) Subtotal 1 ($)
Subtotal 2: $
Size Quantity Price ($)
Do you want to be our agent and get a lower discount?
Please contact us:
Please contact us: