HTR1B (GeneName), 5-hydroxytryptamine receptor 1B (ProteinName), 5HT1B_CANFA.
Dog HTR1B/ 5-hydroxytryptamine receptor 1B Recombinant Protein
5-HT-1B,5-HT1B,5-HTR1B,5-HT1D subtype beta,Serotonin receptor 1B
>90% by SDS-PAGE
Please contact the technician for more information.
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
Store at -20°C. (Avoid repeated freezing and thawing.)
R&D Technical Data
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This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
Cell membrane Multi-pass membrane protein
MEAAGAPCAP | PPPAGSQTGA | PPANLSSAPH | NCSAEGYIYQ | DSVALPWKVL |
LVILLALITL | ATTLSNAFVI | ATVYRTRKLH | TPANYLIASL | AVTDLLVSIL |
VMPISTMYTV | TGRWTLGQVV | CDLWLSSDIT | CCTASILHLC | VIALDRYWAI |
TDAVEYSAKR | TPKRAAVMIA | LVWVFSISIS | LPPFFWRQAK | AEEEVSDCVV |
NTDHILYTVY | STVGAFYFPT | LLLIALYGRI | YVEARSRILK | QTPNRTGKRL |
TRAQLITDSP | GSTSSVTSVN | SRAPDVPSES | GSPVYVNQVK | VRVSDALLEK |
KKLMAARERK | ATKTLGIILG | AFIVCWLPFF | IISLVMPICK | DACWFHLAIF |
DFFTWLGYLN | SLINPIIYTM | SNEDFKQAFH | KLIRFKCAG
This product has not yet been referenced specifically in any publications.
"Lack of association between five serotonin metabolism-related genes and medication overuse headache."
"[Association study of HTR1A and HTR1B with adolescent idiopathic scoliosis]."
"Comorbidity between bipolar disorder and alcohol use disorder: association of dopamine and serotonin gene polymorphisms."
"Fluoxetine response in impulsive-aggressive behavior and serotonin transporter polymorphism in personality disorder."
"Functional polymorphisms in the serotonin 1B receptor gene (HTR1B) predict self-reported anger and hostility among young men."
"SSRI response in depression may be influenced by SNPs in HTR1B and HTR1A."
"An association study of the serotonin transporter and receptor genes with the suicidal ideation of major depression in a Chinese Han population."
"Association analysis of serotonin receptor 1B (HTR1B) and brain-derived neurotrophic factor gene polymorphisms in Borderline personality disorder."
"The relationship between serotonin receptor 1B polymorphisms A-161T and alcohol dependence."
"HTR1B and HTR2C in autism spectrum disorders in Brazilian families."
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