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Home  >  Protein  >  Human EPB41 Recombinant Protein
EPB41 (GeneName), Protein 4.1 (ProteinName), 41_HUMAN.
Product Name:

Human EPB41/ Protein 4.1 Recombinant Protein

 
Cat.#:

R11605h

Brand:
EIAab®
Regulatory Status:
Alternative:

P4.1,4.1R,Band 4.1,EPB4.1,E41P

Source:
E.coli
Species:
Human
Tags:
His
Sequence:
611-864aa
Predicted Molecular Mass:
27.94 kDa (monomer)
Purity:
Greater than 95% by SDS-PAGE
Concentration:
Reconstitution Dependent
Form:
Liquid
Endotoxin Level:
Please contact the technician for more information.
Applications:
Storage Buffer:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
Storage:
Store at -20°C. (Avoid repeated freezing and thawing.)
Research Area:
-
  • Human EPB41 Protein
  • Human EPB41 Protein
  • Human EPB41 Protein
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Product Datasheets
Datasheet:
MSDS:


R&D Technical Data
Human EPB41 Protein
The PCR product of human EPB41 gene was determined by 1% Agarose stained with EB.
Human EPB41 Protein
Recombinant human EPB41 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
Genomic View
Cytogenetic band: 1p35.3 by HGNC 1p35.3 by Entrez Gene 1p35.3 by Ensembl
EPB41 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
General Annotation


Sub Unit:
Binds with a high affinity to glycophorin and with lower affinity to band III protein. Associates with the nuclear mitotic apparatus. Binds calmodulin, CENPJ and DLG1. Also found to associate with contractile apparatus and tight junctions.


Function:
Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes.


Subcellular Location:
Cytoplasm Cytoskeleton Cytoplasm Cell cortex Nucleus


This product has not yet been referenced specifically in any publications.
Publishing research using this product ?
Please let us know and we will provide a credit for your next order.

[1].
"An alternative domain containing a leucine-rich sequence regulates nuclear cytoplasmic localization of protein 4.1R."

[2].
"Protein 4.1R core domain structure and insights into regulation of cytoskeletal organization."

[3].
"Cortical dynein and asymmetric membrane elongation coordinately position the spindle in anaphase."

[4].
"Identification of SNP markers on 1p36 and association analysis of EPB41 with mandibular prognathism in a Chinese population."

[5].
"Marked difference in membrane-protein-binding properties of the two isoforms of protein 4.1R expressed at early and late stages of erythroid differentiation."
Sample Data
Sample Data
Sample Data
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