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EPB41 (基因名), Protein 4.1 (蛋白名), 41_HUMAN.
产品名称:

Human EPB41/ Protein 4.1 Recombinant Protein
蛋白质4.1

货号:

R11605h

商标:
EIAab®
监管等级:
别名:

4.1R, Band 4.1, EPB4.1, P4.1, E41P

序列号:
P11171
来源:
E.coli
种属:
Human
标签:
His
序列:
611-864aa
预估分子量:
27.94 kDa (monomer)
纯度:
Greater than 95% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
  • Human EPB41 Protein
  • Human EPB41 Protein
  • Human EPB41 Protein
规格 & 价格: cart
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Human EPB41 Protein
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human EPB41 Protein
The PCR product of human EPB41 gene was determined by 1% Agarose stained with EB.
Human EPB41 Protein
Recombinant human EPB41 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 1p35.3 by HGNC 1p35.3 by Entrez Gene 1p35.3 by Ensembl
EPB41 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Binds with a high affinity to glycophorin and with lower affinity to band III protein. Associates with the nuclear mitotic apparatus. Binds calmodulin, CENPJ and DLG1. Also found to associate with contractile apparatus and tight junctions.


功能:
Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes.


亚细胞位置:
Cytoplasm Cytoskeleton Cytoplasm Cell cortex Nucleus


该产品尚未在任何出版物中被引用。

[1].
"An alternative domain containing a leucine-rich sequence regulates nuclear cytoplasmic localization of protein 4.1R."

[2].
"Protein 4.1R core domain structure and insights into regulation of cytoskeletal organization."

[3].
"Cortical dynein and asymmetric membrane elongation coordinately position the spindle in anaphase."

[4].
"Identification of SNP markers on 1p36 and association analysis of EPB41 with mandibular prognathism in a Chinese population."

[5].
"Marked difference in membrane-protein-binding properties of the two isoforms of protein 4.1R expressed at early and late stages of erythroid differentiation."
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