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Home  >  Protein  >  Human MPG Recombinant Protein
MPG (GeneName), DNA-3-methyladenine glycosylase (ProteinName), 3MG_HUMAN.
Product Name:

Human MPG/ DNA-3-methyladenine glycosylase Recombinant Protein

 
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

3-alkyladenine DNA glycosylase,3-methyladenine DNA glycosidase,ADPG,N-methylpurine-DNA glycosylase,AAG,ANPG,MID1

Source:
E.coli
Species:
Human
Tags:
His
Purity:
>90% by SDS-PAGE
Concentration:
Reconstitution Dependent
Form:
Liquid
Storage Buffer:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
Storage:
Store at -20°C. (Avoid repeated freezing and thawing.)
Research Area:
-
Human MPG Protein
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Human MPG Protein
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Product Datasheets
Instruction:
MSDS:


Genomic View
Cytogenetic band: 16p13.3 by HGNC 16p13.3 by Entrez Gene 16p13.3 by Ensembl
MPG Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
General Annotation


Sub Unit:
Binds MBD1. Binds SSBP1.


Function:
Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.


Subcellular Location:
Cytoplasm Mitochondrion matrix Mitochondrion nucleoid Nucleus


This product has not yet been referenced specifically in any publications.
Publishing research using this product ?
Please let us know and we will provide a credit for your next order.

[1].
"Cloning and expression in Escherichia coli of a human cDNA encoding the DNA repair protein N-methylpurine-DNA glycosylase."

[2].
"Methylated DNA-binding domain 1 and methylpurine-DNA glycosylase link transcriptional repression and DNA repair in chromatin."

[3].
"Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision."

[4].
"Homology of a 130-kb region enclosing the alpha-globin gene cluster, the alpha-locus controlling region, and two non-globin genes in human and mouse."

[5].
"Structure of the human 3-methyladenine DNA glycosylase gene and localization close to the 16p telomere."

[6].
"Cloning and characterization of a 3-methyladenine DNA glycosylase cDNA from human cells whose gene maps to chromosome 16."

[7].
"Alkyladenine DNA glycosylase (AAG) localizes to mitochondria and interacts with mitochondrial single-stranded binding protein (mtSSB)."

[8].
"Hopping enables a DNA repair glycosylase to search both strands and bypass a bound protein."

[9].
"Association between genetic variants in the base excision repair pathway and outcomes after hematopoietic cell transplantations."

[10].
"Variation within DNA repair pathway genes and risk of multiple sclerosis."
Sample Data
Sample Data
Sample Data
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