HAAO (GeneName), 3-hydroxyanthranilate 3,4-dioxygenase (ProteinName), 3HAO_HUMAN.
Human HAAO/ 3-hydroxyanthranilate 3,4-dioxygenase Recombinant Protein
3-hydroxyanthranilate oxygenase,3-HAO,3-hydroxyanthranilic acid dioxygenase,HAD
>90% by SDS-PAGE
Please contact the technician for more information.
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
Store at -20°C. (Avoid repeated freezing and thawing.)
R&D Technical Data
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Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
MERRLGVRAW | VKENRGSFQP | PVCNKLMHQE | QLKVMFIGGP | NTRKDYHIEE |
GEEVFYQLEG | DMVLRVLEQG | KHRDVVIRQG | EIFLLPARVP | HSPQRFANTV |
GLVVERRRLE | TELDGLRYYV | GDTMDVLFEK | WFYCKDLGTQ | LAPIIQEFFS |
SEQYRTGKPI | PDQLLKEPPF | PLSTRSIMEP | MSLDAWLDSH | HRELQAGTPL |
SLFGDTYETQ | VIAYGQGSSE | GLRQNVDVWL | WQLEGSSVVT | MGGRRLSLAP |
DDSLLVLAGT | SYAWERTQGS | VALSVTQDPA | CKKPLG
This product has not yet been referenced specifically in any publications.
"Molecular cloning and functional expression of human 3-hydroxyanthranilic-acid dioxygenase."
"NAD Deficiency, Congenital Malformations, and Niacin Supplementation."
"Crystal structures of human 3-hydroxyanthranilate 3,4-dioxygenase with native and non-native metals bound in the active site."
"Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts."
"Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling."
"Identification of candidate epigenetic biomarkers for ovarian cancer detection."
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
"Cloning of human 3-hydroxyanthranilic acid dioxygenase in Escherichia coli: characterisation of the purified enzyme and its in vitro inhibition by Zn2+."
"A proteome-scale map of the human interactome network."
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