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Home  >  Protein  >  Rat Sh3bp5 Recombinant Protein
Sh3bp5 (GeneName), SH3 domain-binding protein 5 (ProteinName), 3BP5_RAT.
Product Name:

Rat Sh3bp5/ SH3 domain-binding protein 5 Recombinant Protein

 
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

SH3BP-5,Vascular endothelial cell-specific protein 18,Sab,Vesp18

Source:
E.coli
Species:
Rat
Tags:
His
Purity:
>90% by SDS-PAGE
Concentration:
Reconstitution Dependent
Form:
Liquid
Endotoxin Level:
Please contact the technician for more information.
Storage Buffer:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
Storage:
Store at -20°C. (Avoid repeated freezing and thawing.)
Research Area:
-
Rat Sh3bp5 Protein
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Product Datasheets
Instruction:
MSDS:


General Annotation


Sub Unit:
Interacts with BTK (PubMed:15158451). Interacts with all isoforms of MAPK8, MAPK9, MAPK10 and MAPK12 (PubMed:15158451). Interacts with GDP-bound and nucleotide-free forms of RAB11A.


Function:
Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.


Subcellular Location:
Mitochondrion


This product has not yet been referenced specifically in any publications.
Publishing research using this product ?
Please let us know and we will provide a credit for your next order.

[1].
"Bruton's tyrosine kinase activity is negatively regulated by Sab, the Btk-SH3 domain-binding protein."

[2].
"Identification and characterization of a novel SH3-domain binding protein, Sab, which preferentially associates with Bruton's tyrosine kinase (BtK)."

[3].
"Structural determinants of Rab11 activation by the guanine nucleotide exchange factor SH3BP5."

[4].
"A probability-based approach for high-throughput protein phosphorylation analysis and site localization."

[5].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[6].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[7].
"Sab (SH3BP5), a novel mitochondria-localized JNK-interacting protein."

[8].
"A new c-Jun N-terminal kinase (JNK)-interacting protein, Sab (SH3BP5), associates with mitochondria."

[9].
"Architecture of the human interactome defines protein communities and disease networks."

[10].
"REI/SH3BP5 protein family: New GEFs for Rab11."
Sample Data
Sample Data
Sample Data
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