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Sh3bp1 (GeneName), SH3 domain-binding protein 1 (ProteinName), 3BP1_MOUSE.
Product Name:

Mouse Sh3bp1/ SH3 domain-binding protein 1 Recombinant Protein

 
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

3BP-1,3bp1

Source:
E.coli
Species:
Mouse
Tags:
His
Purity:
>90% by SDS-PAGE
Concentration:
Reconstitution Dependent
Form:
Liquid
Storage Buffer:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
Storage:
Store at -20°C. (Avoid repeated freezing and thawing.)
Research Area:
-
Mouse Sh3bp1 Protein
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Product Datasheets
Instruction:
MSDS:


General Annotation


Sub Unit:
N/A


Function:
Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac.


Subcellular Location:
N/A


This product has not yet been referenced specifically in any publications.
Publishing research using this product ?
Please let us know and we will provide a credit for your next order.

[1].
"The DNA sequence of human chromosome 22."

[2].
"Phosphoinositide 3-kinase enables phagocytosis of large particles by terminating actin assembly through Rac/Cdc42 GTPase-activating proteins."

[3].
"An image-based RNAi screen identifies SH3BP1 as a key effector of Semaphorin 3E-PlexinD1 signaling."

[4].
"A novel Rac1 GAP splice variant relays poly-Ub accumulation signals to mediate Rac1 inactivation."

[5].
"Epithelial junction formation requires confinement of Cdc42 activity by a novel SH3BP1 complex."

[6].
"SH3BP1, an exocyst-associated RhoGAP, inactivates Rac1 at the front to drive cell motility."

[7].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[8].
"A genome annotation-driven approach to cloning the human ORFeome."

[9].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[10].
"Identification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1."
Sample Data
Sample Data
Sample Data
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