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SFN (GeneName), 14-3-3 protein sigma (ProteinName), 1433S_BOVIN.
Product Name:

Bovine SFN/ 14-3-3 protein sigma Recombinant Protein

 
Cat.#:

R15106b

Brand:
EIAab®
Regulatory Status:
Alternative:

Stratifin

Source:
E.coli
Species:
Bovine
Tags:
His
Purity:
>90% by SDS-PAGE
Concentration:
Reconstitution Dependent
Form:
Liquid
Endotoxin Level:
Please contact the technician for more information.
Storage Buffer:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
Storage:
Store at -20°C. (Avoid repeated freezing and thawing.)
Research Area:
Cancer
Bovine SFN Protein
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Product Datasheets
Instruction:
MSDS:


R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
General Annotation


Sub Unit:
Homodimer. Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29 and VPS35. Interacts with KRT17. Interacts with GAB2 and SAMSN1 (By similarity). Interacts with SRPK2 (By similarity). Interacts with COPS6 (By similarity). Interacts with RFWD2; this interaction leads to proteasomal degradation (By similarity). Interacts with the 'Thr-369' phosphorylated form of DAPK2 (By similarity). Interacts with PI4KB (By similarity). Interacts with SLITRK1.


Function:
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.


Subcellular Location:
Cytoplasm Nucleus Secreted May be secreted by a non-classical secretory pathway.


This product has not yet been referenced specifically in any publications.
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Sample Data
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