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Home  >  Protein  >  Mouse Ywhah Recombinant Protein
Ywhah (GeneName), 14-3-3 protein eta (ProteinName), 1433F_MOUSE.
Product Name:

Mouse Ywhah/ 14-3-3 protein eta Recombinant Protein

 
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Source:
E.coli
Species:
Mouse
Tags:
His
Purity:
>90% by SDS-PAGE
Concentration:
Reconstitution Dependent
Form:
Liquid
Storage Buffer:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
Storage:
Store at -20°C. (Avoid repeated freezing and thawing.)
Research Area:
Cancer
Mouse Ywhah Protein
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Mouse Ywhah Protein
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Product Datasheets
Instruction:
MSDS:


General Annotation


Sub Unit:
Homodimer (By similarity). Interacts with many nuclear hormone receptors and cofactors including AR, ESR1, ESR2, MC2R, NR3C1, NRIP1, PPARBP and THRA. Interacts with ABL1 (phosphorylated form); the interaction retains it in the cytoplasm. Weakly interacts with CDKN1B (By similarity). Interacts with ARHGEF28 and CDK16. Interacts with KCNK18 in a phosphorylation-dependent manner. Interacts with SAMSN1. Interacts with the 'Ser-241' phosphorylated form of PDPK1 (By similarity). Interacts with the 'Thr-369' phosphorylated form of DAPK2 (PubMed:26047703). Interacts with PI4KB, TBC1D22A and TBC1D22B (By similarity). Interacts with SLITRK1.


Function:
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.


Subcellular Location:
Cytoplasm


This product has not yet been referenced specifically in any publications.
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[1].
"Systematic screening of the 14-3-3 eta (eta) chain gene for polymorphic variants and case-control analysis in schizophrenia."

[2].
"14-3-3 protein eta chain gene (YWHAH) polymorphism and its genetic association with schizophrenia."

[3].
"The human and bovine 14-3-3 eta protein mRNAs are highly conserved in both their translated and untranslated regions."

[4].
"cDNA cloning and chromosome assignment of the gene for human brain 14-3-3 protein eta chain."

[5].
"ACBD3 interaction with TBC1 domain 22 protein is differentially affected by enteroviral and kobuviral 3A protein binding."

[6].
"Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study."

[7].
"Family-based association of YWHAH in psychotic bipolar disorder."

[8].
"SLITRK1 binds 14-3-3 and regulates neurite outgrowth in a phosphorylation-dependent manner."

[9].
"Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein."

[10].
"Structural basis for protein-protein interactions in the 14-3-3 protein family."
Sample Data
Sample Data
Sample Data
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