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TAP (Shorten Name),
Product Name:

Mouse TAP/ Trypsinogen Activation Peptide,TAP Recombinant Protein

 
Cat.#:

R0634m

Brand:
EIAab®
Regulatory Status:
Source:
E.coli
Species:
Mouse
Tags:
His
Purity:
>90% by SDS-PAGE
Concentration:
Reconstitution Dependent
Form:
Liquid
Endotoxin Level:
Please contact the technician for more information.
Storage Buffer:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
Storage:
Store at -20°C. (Avoid repeated freezing and thawing.)
Research Area:
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Mouse TAP Protein
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Product Datasheets
Instruction:
MSDS:


R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
General Annotation


Sub Unit:
N/A


Function:
Trypsinogen-activation peptide (TAP) is a small peptide that is released when trypsinogen is activated to trypsin. Under physiologic conditions, activation of trypsinogen occurs in the intestinal lumen and is catalyzed by enteropeptidase (formerly known as enterokinase). In the intestinal lumen, TAP is quickly degraded by peptidases of the brush border membrane. In pancreatitis, trypsinogen is prematurely activated within pancreatic acinar cells, and TAP is released into the peripheral circulation. Although TAP is quickly excreted through the kidneys, with a circulating half-life of less than 8 min, significant increases in plasma and urine TAP concentrations have been reported in canine and human patients with acute pancreatitis. An assay of TAP has been shown to be useful for the diagnosis and staging of pancreatitis in humans and dogs. Also, measurement of TAP in plasma and urine has been evaluated in experimental rodent and feline models of pancreatitis and has been shown to be useful in assessing pancreatic inflammation in those species.


Location:
N/A


This product has not yet been referenced specifically in any publications.
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