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PFKFB4 (GeneName), 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (ProteinName), f264_human.
Product Name:

Human PFKFB4/ 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 ELISA Kit

Cat.#:

E10217h

Brand:
EIAab®
Regulatory Status:
Alternative:

6PF-2-K/Fru-2, 6-P2ase 4, 6PF-2-K/Fru-2, 6-P2ase testis-type isozyme

Detection Method:
ELISA
Assay Type:
Sandwich
Detection Range:
0.156-10ng/mL
Sensitivity:
0.039ng/mL
Specificity:
Natural and recombinant human 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Assay Procedure:
Assay Procedure
Research Area:
-
Human PFKFB4 ELISA Kit
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Human PFKFB4 ELISA Kit
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Product Datasheets
Datasheet: Down Datasheet
Instruction: Down Instruction
MSDS: MSDS


General Annotation


Sub Unit:
Homodimer.


Function:
Synthesis and degradation of fructose 2,6-bisphosphate.


Subcellular Location:
N/A


This product has not yet been referenced specifically in any publications.

[1].
"Cloning, expression and chromosomal localization of a human testis 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene."

[2].
"Specific expression of pfkfb4 gene in spermatogonia germ cells and analysis of its 5'-flanking region."

[3].
"Hypoxia induces transcription of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-4 gene via hypoxia-inducible factor-1alpha activation."

[4].
"Cloning of cDNA encoding for a novel isozyme of fructose 6-phosphate, 2-kinase/fructose 2,6-bisphosphatase from human placenta."

[5].
"Fructose-2,6-bisphosphate synthesis by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) is required for the glycolytic response to hypoxia and tumor growth."

[6].
"Hypoxic regulation of PFKFB-3 and PFKFB-4 gene expression in gastric and pancreatic cancer cell lines and expression of PFKFB genes in gastric cancers."

[7].
"Overexpression of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-4 in the human breast and colon malignant tumors."

[8].
"Splice isoform of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-4: expression and hypoxic regulation."

[9].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[10].
"Analysis of Malignant Melanoma Cell Lines Exposed to Hypoxia Reveals the Importance of PFKFB4 Overexpression for Disease Progression."
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