BMP15 (GeneName), Bone morphogenetic protein 15 (ProteinName), bmp15_bovin.
Bovine BMP15/ Bone morphogenetic protein 15 ELISA Kit
Natural and recombinant bovine Bone morphogenetic protein 15
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
E1469b is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the A Disintegrin and Metalloprotease 30 (Bone morphogenetic protein 15) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Bone morphogenetic protein 15. The ELISA analytical biochemical technique of the E1469b kit is based on Bone morphogenetic protein 15 antibody-Bone morphogenetic protein 15 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Bone morphogenetic protein 15 antigen targets in samples. The ELISA Kit is designed to detect native, recombinant, Bone morphogenetic protein 15. Appropriate sample types may include undiluted human body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.
May be involved in follicular development. Seems to be an oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth.
MVLLSILRIL | LLWGLVLFME | HRVQMTQVGQ | PSIAHLPEAP | TLPLIQELLE |
EAPGKQQRKP | RILGHPLRYM | LELYQRSADA | SGHPRENRTI | GATMVRLVRP |
LASVARPLRG | SWHIQTLDFP | LRPNRVAYQL | VRATVVYRHQ | LHLTHSHLSC |
HVEPWVQKSP | TNHFPSSGRG | SSKPSLLPKA | WTEMDIMEHV | GQKLWNHKGR |
RVLRLRFVCQ | QPRGSEVREF | WWHGTSSLDT | VFLLLYFNDT | QSVQKTKPLP |
KGLKEFTEKD | PSLLLRRARQ | AGSIASEVPG | PSREHDGPES | NLCSLHPFQV |
SFQQLGWDHW | IIAPHLYTPN | YCKGVCPRVL | HYGLNSPNHA | IIQNLVNELV |
DQSVPQPSCV | PYKYVPISIL | LIEANGSILY | KEYEGMIAQS | CTCR
This product has not yet been referenced specifically in any publications.
"BMP15 mutations associated with primary ovarian insufficiency cause a defective production of bioactive protein."
"Mutations and sequence variants in GDF9 and BMP15 in patients with premature ovarian failure."
"Missense mutations in the BMP15 gene are associated with ovarian failure."
"The bone morphogenetic protein 15 gene is X-linked and expressed in oocytes."
"Analyses of growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) mutation in Chinese women with premature ovarian failure."
"Variants of the BMP15 gene in a cohort of patients with premature ovarian failure."
"Characterization of the post-translational modification of recombinant human BMP-15 mature protein."
"Sequence variants in exons of the BMP-15 gene in Chinese patients with premature ovarian failure."
"Mutational analysis of BMP15 and GDF9 as candidate genes for premature ovarian failure."
"Identification of new variants of human BMP15 gene in a large cohort of women with premature ovarian failure."
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