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Mpp5 (基因名), MAGUK p55 subfamily member 5 (蛋白名), MPP5_MOUSE.
产品名称:

Mouse Mpp5/ MAGUK p55 subfamily member 5 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Protein associated with Lin-7 1, Pals1

检测方法:
ELISA
特异性:
Natural and recombinant mouse MAGUK p55 subfamily member 5
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Mouse Mpp5 ELISA Kit
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Mouse Mpp5 ELISA Kit
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亚单元:
Heterodimer with MPP1. Interacts with MPP7. Forms a complex with CRB1 and MPP4. Component of a complex whose core is composed of ARHGAP17, AMOT, MPP5/PALS1, PATJ and PARD3/PAR3 (By similarity). Interacts with CRB3, EZR, PATJ, LIN7C, MPDZ, PARD6B and SC6A1.


功能:
May play a role in tight junctions biogenesis and in the establishment of cell polarity in epithelial cells. May modulate SC6A1/GAT1-mediated GABA uptake by stabilizing the transporter. Required for localization of EZR to the apical membrane of parietal cells and may play a role in the dynamic remodeling of the apical cytoskeleton.


亚细胞位置:
Cell membrane Peripheral membrane protein Endomembrane system Peripheral membrane protein Cell junction Tight junction Localized to the tight junctions of epithelial cells and a subset of intracellular vesicles. Localized to the Purkinje cell body and axon. Localized to apical membrane domains of the outer limiting membrane junctions in the retina. Colocalizes with MPP1 in the retina at the outer limiting membrane (OLM) (By similarity).


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