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Mpp2 (基因名), MAGUK p55 subfamily member 2 (蛋白名), MPP2_RAT.
产品名称:

Rat Mpp2/ MAGUK p55 subfamily member 2 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Protein MPP2, rCG_34691

检测方法:
ELISA
特异性:
Natural and recombinant rat MAGUK p55 subfamily member 2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Rat Mpp2 ELISA Kit
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Rat Mpp2 ELISA Kit
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通用注释


亚单元:
Can homomultimerise (PubMed:27756895). Interacts with CACNG2 (PubMed:27756895). Interacts (via the SH3-Guanylate kinase-like sub-module) with DLG4/PSD95 and DLGAP1/GKAP (PubMed:27756895). Interacts (via the PDZ domain) with CADM1 (via C-terminus) (PubMed:27756895). Interacts with KCNN2/SK2 (via N-terminal domain) (By similarity). Interacts with SRC.


功能:
Postsynaptic MAGUK scaffold protein that links CADM1 cell adhesion molecules to core components of the postsynaptic density (PubMed:27756895). In CA1 pyramidal neurons, required for synaptic KCNN2-containing channel function and long-term potentiation expression (By similarity). Seems to negatively regulate SRC function in epithelial cells.


亚细胞位置:
Cell projection Dendrite Cell projection Dendritic spine membrane Cell junction Synapse Postsynaptic cell membrane Postsynaptic density Cytoplasm Cytoskeleton Membrane Prominently expressed in the post-synaptic densities of dendritic spines, is also detected in dendritic shafts.


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