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首页  >  酶联免疫试剂盒  >  Mouse Cdc25a ELISA Kit
Cdc25a (基因名), M-phase inducer phosphatase 1 (蛋白名), MPIP1_MOUSE.
产品名称:

Mouse Cdc25a/ M-phase inducer phosphatase 1 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Dual specificity phosphatase Cdc25A, Cdc25m3

检测方法:
ELISA
特异性:
Natural and recombinant mouse M-phase inducer phosphatase 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cancer
Mouse Cdc25a ELISA Kit
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Mouse Cdc25a ELISA Kit
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产品说明书


通用注释


亚单元:
Interacts with CCNB1/cyclin B1. Interacts with YWHAE/14-3-3 epsilon when phosphorylated. Interacts with CUL1 specifically when CUL1 is neddylated and active. Interacts with BTRC/BTRCP1 and FBXW11/BTRCP2. Interactions with CUL1, BTRC and FBXW11 are enhanced upon DNA damage. Interacts with PIM1. Interacts with CHEK2; mediates CDC25A phosphorylation and degradation in response to infrared-induced DNA damages (By similarity). Interacts with HSP90AB1; prevents heat shock-mediated CDC25A degradation and contributes to cell cycle progression.


功能:
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro (By similarity). Phosphorylation by PIM1 leads to an increase in phosphatase activity.


亚细胞位置:
N/A


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