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Mpdz (基因名), Multiple PDZ domain protein (蛋白名), MPDZ_MOUSE.
产品名称:

Mouse Mpdz/ Multiple PDZ domain protein ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Multi-PDZ domain protein 1, Mupp1

检测方法:
ELISA
特异性:
Natural and recombinant mouse Multiple PDZ domain protein
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Mouse Mpdz ELISA Kit
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Mouse Mpdz ELISA Kit
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通用注释


亚单元:
Interacts with CLDN5, DLG4, GRIN1, SYNGAP1, CAMK2A and CAMK2B, HTR2A, HTR2B, HTR2C, PLEKHA1/TAPP1 and PLEKHA2/TAPP2 (By similarity). Interacts with F11R/JAM, CLDN1, NG2, CXADR, CRB1, MPP4 and MPP5. Interacts with FAT4 (via cytoplasmic domain). Interacts with the adenovirus type 9 E4-ORF1 oncoprotein. Interacts with DLL1 (PubMed:15509766).


功能:
Interacts with HTR2C and provokes its clustering at the cell surface. Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses.


亚细胞位置:
Cell membrane Peripheral membrane protein Cytoplasmic side Apical cell membrane Peripheral membrane protein Cytoplasmic side Cell junction Synapse Postsynaptic cell membrane Postsynaptic density Cell projection Dendrite Cell junction Tight junction Cell junction Synapse Cell junction Synapse Synaptosome Colocalizes with HTR2C on the apical membrane of epithelial choroid plexus cells. Highly enriched in postsynaptic densities (PSD). Localized to punctae on dendrites of hippocampal neurons and colocalizes with the synaptic marker DLG4. Enriched at the tight junctions of epithelial cells. Association to the tight junctions depends on CXADR (By similarity). In the retina, localizes to the sub-apical region adjacent to the adherens junction complex at the outer limiting membrane. Localized mainly in the Schmidt-Lanterman incisures of myelinating Schwann cells.


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