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首页  >  酶联免疫试剂盒  >  Human MORC3 ELISA Kit
MORC3 (基因名), MORC family CW-type zinc finger protein 3 (蛋白名), MORC3_HUMAN.
产品名称:

Human MORC3/ MORC family CW-type zinc finger protein 3 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Nuclear matrix protein 2, Zinc finger CW-type coiled-coil domain protein 3, KIAA0136, NXP2, ZCWCC3

检测方法:
ELISA
特异性:
Natural and recombinant human MORC family CW-type zinc finger protein 3
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cancer
Human MORC3 ELISA Kit
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Human MORC3 ELISA Kit
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产品说明书


通用注释


亚单元:
Homodimer (PubMed:17332504). The sumoylated form interacts with PML (via SUMO-interacting motif) (PubMed:20501696, PubMed:17332504). Interacts with PT53 (PubMed:17332504). Interacts with influenza A virus PA and PB1 polymerase subunits during infection (PubMed:26202233).


功能:
Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism (PubMed:20501696). Sumoylated MORC3-NBs can also associate with PML-NBs (PubMed:20501696). Recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity (PubMed:17332504). Binds RNA in vitro (PubMed:11927593). May be required for influenza A transcription during viral infection (PubMed:26202233).


亚细胞位置:
Nucleus Nucleoplasm Nucleus matrix Nucleus PML body Also found in PML-independent nuclear bodies. Localization to nuclear bodies is ATP-dependent.


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