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首页  >  酶联免疫试剂盒  >  Human MOBKL1A ELISA Kit
MOBKL1A (基因名), Mps one binder kinase activator-like 1A (蛋白名), MOL1A_HUMAN.
产品名称:

Human MOBKL1A/ Mps one binder kinase activator-like 1A ELISA Kit
Mps - 1结合剂激酶激活因子样1A

货号:

E2913h

商标:
EIAab®
监管等级:
别名:

Mob1 homolog 1A, Mob1A, Mob1B, Protein Mob4A, MOB4A

检测方法:
ELISA
特异性:
Natural and recombinant human Mps one binder kinase activator-like 1A
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Human MOBKL1A ELISA Kit
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Human MOBKL1A ELISA Kit
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产品说明书


通用注释


亚单元:
Binds STK38L. Interacts with LATS1 and LATS2.


功能:
Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38L.


亚细胞位置:
Cytoplasm Nucleus


该产品尚未在任何出版物中被引用。
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