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MYL2 (基因名), Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (蛋白名), MLRV_HUMAN.
产品名称:

Human MYL2/ Myosin regulatory light chain 2, ventricular/cardiac muscle isoform ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Cardiac myosin light chain 2, Myosin light chain 2, slow skeletal/ventricular muscle isoform, Ventricular myosin light chain 2, MLC-2s/v, MLC-2, MLC2

检测方法:
ELISA
特异性:
Natural and recombinant human Myosin regulatory light chain 2, ventricular/cardiac muscle isoform
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Human MYL2 ELISA Kit
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Human MYL2 ELISA Kit
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通用注释


亚单元:
Myosin is a hexamer of 2 heavy chains and 4 light chains. Interacts with MYOC (PubMed:11773029).


功能:
Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin binding sites to sustain thin filament activation as a means to fine-tune myofilament calcium sensitivity to force (By similarity). During cardiogenesis plays an early role in cardiac contractility by promoting cardiac myofibril assembly.


亚细胞位置:
Cytoplasm Myofibril Sarcomere A band


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