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首页  >  酶联免疫试剂盒  >  Bovine MAP1LC3A ELISA Kit
MAP1LC3A (基因名), Microtubule-associated proteins 1A/1B light chain 3A (蛋白名), MLP3A_BOVIN.
产品名称:

Bovine MAP1LC3A/ Microtubule-associated proteins 1A/1B light chain 3A ELISA Kit
HumanMicrotubule-associatedproteins1A/1Blightchain3A

货号:

E2879b

商标:
EIAab®
监管等级:
别名:

Autophagy-related protein LC3 A, Autophagy-related ubiquitin-like modifier LC3 A, MAP1 light chain 3-like protein 1, MAP1A/MAP1B light chain 3 A, MAP1A/MAP1B LC3 A, Microtubule-associated protein 1 light chain 3 alpha

检测方法:
ELISA
特异性:
Natural and recombinant bovine Microtubule-associated proteins 1A/1B light chain 3A
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cancer
Bovine MAP1LC3A ELISA Kit
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Bovine MAP1LC3A ELISA Kit
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产品说明书


通用注释


亚单元:
3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins (By similarity). Interacts with TP53INP1 and TP53INP2. Directly interacts with SQSTM1; this interaction leads to MAP1LC3A recruitment to inclusion bodies containing polyubiquitinated protein aggregates and to inclusion body degradation by autophagy. Interacts with ATG13. Interacts with ULK1. Interacts with TBC1D5. Found in a complex with UBQLN1 and UBQLN2. Interacts with UBQLN4 (via STI1 1 and 2 domains). Interacts with UBQLN1 in the presence of UBQLN4. Interacts with TRIM5. Interacts with MEFV. Interacts with FAM134A, FAM134B and FAM134C.


功能:
Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.


亚细胞位置:
Cytoplasm Cytoskeleton Endomembrane system Lipid-anchor Cytoplasmic vesicle Autophagosome membrane Lipid-anchor Cytoplasmic vesicle Autophagosome LC3-II binds to the autophagic membranes.


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