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首页  >  酶联免疫试剂盒  >  Human MLL3 ELISA Kit
MLL3 (基因名), Histone-lysine N-methyltransferase MLL3 (蛋白名), MLL3_HUMAN.
产品名称:

Human MLL3/ Histone-lysine N-methyltransferase MLL3 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Homologous to ALR protein, Lysine N-methyltransferase 2C, KMT2C, Myeloid/lymphoid or mixed-lineage leukemia protein 3, HALR, KIAA1506, KMT2C

检测方法:
ELISA
特异性:
Natural and recombinant human Histone-lysine N-methyltransferase MLL3
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Human MLL3 ELISA Kit
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Human MLL3 ELISA Kit
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产品说明书


通用注释


亚单元:
Component of the MLL2/MLL3 complex (also named ASCOM complex), at least composed of MLL2, MLL3, ASH2L, RBBP5, DPY30, NCOA6, WDR5, MEN1, KDM6A and PAXIP1/PTIP. Component of the MLL3/MLL4 complex at least composed of MLL3, MLL4, ASH2L, RBBP5, DPY30, WDR5, NCOA6, KDM6A, PAXIP1/PTIP and C16orf53/PA1. Interacts with histone H3.


功能:
Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/MLL3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.


亚细胞位置:
Nucleus


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