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首页  >  酶联免疫试剂盒  >  Mouse Mll2 ELISA Kit
Mll2 (基因名), Histone-lysine N-methyltransferase MLL2 (蛋白名), MLL2_MOUSE.
产品名称:

Mouse Mll2/ Histone-lysine N-methyltransferase MLL2 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Lysine N-methyltransferase 2B, KMT2B

检测方法:
ELISA
特异性:
Natural and recombinant mouse Histone-lysine N-methyltransferase MLL2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Mouse Mll2 ELISA Kit
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Mouse Mll2 ELISA Kit
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产品说明书


通用注释


亚单元:
Component of the MLL2/MLL3 complex (also named ASCOM complex), at least composed of MLL2, MLL3, ASH2L, RBBP5, DPY30, NCOA6, WDR5, MEN1, KDM6A and PAXIP1/PTIP. Interacts with NFE2. Interacts with ESR1; interaction is direct.


功能:
Histone methyltransferase. Methylates 'Lys-4' of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. Plays a central role in beta-globin locus transcription regulation by being recruited by NFE2. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription (By similarity). Plays an important role in controlling bulk H3K4me during oocyte growth and preimplantation development. Required during the transcriptionally active period of oocyte growth for the establishment and/or maintenance of bulk H3K4 trimethylation (H3K4me3), global transcriptional silencing that preceeds resumption of meiosis, oocyte survival and normal zygotic genome activation.


亚细胞位置:
Nucleus


该产品尚未在任何出版物中被引用。
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