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首页  >  酶联免疫试剂盒  >  Mouse Mlkl ELISA Kit
Mlkl (基因名), Mixed lineage kinase domain-like protein (蛋白名), MLKL_MOUSE.
产品名称:

Mouse Mlkl/ Mixed lineage kinase domain-like protein ELISA Kit
混合谱系激酶结构域样蛋白

货号:

E1747m

商标:
EIAab®
监管等级:
检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.312-20ng/mL
灵敏度:
0.18ng/mL
特异性:
Natural and recombinant mouse Mixed lineage kinase domain-like protein
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Mouse Mlkl ELISA Kit
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Mouse Mlkl ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS


通用注释


亚单元:
Homotrimer; forms homotrimers on necroptosis induction. Upon TNF-induced necrosis, forms in complex with PGAM5, RIPK1 and RIPK3. Within this complex, may play a role in the proper targeting of RIPK1/RIPK3 to its downstream effector PGAM5 (By similarity). Interacts with RIPK3; the interaction is direct.


功能:
Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.


亚细胞位置:
Cytoplasm Cell membrane Localizes to the cytoplasm and translocates to the plasma membrane on necroptosis induction.


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