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Tmem67 (基因名), Meckelin (蛋白名), MKS3_MOUSE.
产品名称:

Mouse Tmem67/ Meckelin ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Meckel syndrome type 3 protein homolog, Transmembrane protein 67, Mks3

检测方法:
ELISA
特异性:
Natural and recombinant mouse Meckelin
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Mouse Tmem67 ELISA Kit
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Mouse Tmem67 ELISA Kit
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通用注释


亚单元:
Interacts with DNAJB9, DNAJC10 and mutated SFTPC (By similarity). Interacts with SYNE2 during the early establishment of cell polarity (By similarity). Part of the tectonic-like complex (also named B9 complex). Interacts (via C-terminus) with FLNA.


功能:
Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition. Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology. Essential for endoplasmic reticulum-associated degradation (ERAD) of surfactant protein C (sftpc).


亚细胞位置:
Cell membrane Multi-pass membrane protein Endoplasmic reticulum membrane Multi-pass membrane protein Cytoplasm Cytoskeleton Cilium basal body Localizes at the transition zone, a region between the basal body and the ciliary axoneme.


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