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TMEM67 (基因名), Meckelin (蛋白名), MKS3_HUMAN.
产品名称:

Human TMEM67/ Meckelin ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Meckel syndrome type 3 protein, Transmembrane protein 67, MKS3

检测方法:
ELISA
特异性:
Natural and recombinant human Meckelin
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Human TMEM67 ELISA Kit
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Human TMEM67 ELISA Kit
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通用注释


亚单元:
Part of the tectonic-like complex (also named B9 complex) (By similarity). Interacts with DNAJB9, DNAJC10 and mutated SFTPC. Interacts with SYNE2 during the early establishment of cell polarity. Interacts (via C-terminus) with FLNA.


功能:
Required for ciliary structure and function. Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). Involved in centrosome migration to the apical cell surface during early ciliogenesis. Involved in the regulation of cilia length and appropriate number through the control of centrosome duplication. Required for cell branching morphology. Essential for endoplasmic reticulum-associated degradation (ERAD) of surfactant protein C (SFTPC).


亚细胞位置:
Cell membrane Multi-pass membrane protein Endoplasmic reticulum membrane Multi-pass membrane protein Cytoplasm Cytoskeleton Cilium basal body Localizes at the transition zone, a region between the basal body and the ciliary axoneme.


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