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Mkks (基因名), McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin (蛋白名), MKKS_MOUSE.
产品名称:

Mouse Mkks/ McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Protein Bbs6 homolog, Bbs6

检测方法:
ELISA
特异性:
Natural and recombinant mouse McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cancer
Mouse Mkks ELISA Kit
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Mouse Mkks ELISA Kit
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通用注释


亚单元:
Component of the BBS/CCT complex composed at least of MKKS, BBS10, BBS12, TCP1, CCT2, CCT3, CCT4, CCT5 AND CCT8. Interacts with STUB1. Interacts with BBS2 (via coiled coil domain). Interacts with CCDC28B. Interacts with BBS12.


功能:
Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (By similarity). May play a role in protein processing in limb, cardiac and reproductive system development. May play a role in cytokinesis.


亚细胞位置:
Cytoplasm Cytoskeleton Microtubule organizing center Centrosome Cytoplasm Cytosol The majority of the protein resides within the pericentriolar material (PCM), a proteinaceous tube surrounding centrioles. During interphase, the protein is confined to the lateral surfaces of the PCM but during mitosis it relocalizes throughout the PCM and is found at the intercellular bridge. The MKSS protein is highly mobile and rapidly shuttles between the cytosol and centrosome (By similarity).


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