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MAPK14 (基因名), Mitogen-activated protein kinase 14 (蛋白名), MK14_CANFA.
产品名称:

Dog MAPK14/ Mitogen-activated protein kinase 14 ELISA Kit
促分裂原活化蛋白激酶14

货号:

E9114d

商标:
EIAab®
监管等级:
别名:

Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, MAP kinase 14, MAPK 14, CSBP1, CSBP2

检测方法:
ELISA
实验类型:
Sandwich
特异性:
Natural and recombinant dog Mitogen-activated protein kinase 14
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Neurosciences
Dog MAPK14 ELISA Kit
规格 & 价格: cart
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Dog MAPK14 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

99-109%

94-103%

101-111%

95-106%

EDTA plasma(n=5)

99-109%

87-97%

93-103%

97-107%

heparin plasma(n=5)

88-98%

 

96-106%

111-123%

115-125%

 

通用注释


亚单元:
Binds to a kinase interaction motif within the protein tyrosine phosphatase, PTPRR. This interaction retains MAPK14 in the cytoplasm and prevents nuclear accumulation. Interacts with FAM48A, SPAG9 and NP60.


功能:
Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO during hypoxic stress.


亚细胞位置:
Cytoplasm Nucleus


该产品尚未在任何出版物中被引用。
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