EIAab
首页  >  酶联免疫试剂盒  >  Rat Mapk7 ELISA Kit
Mapk7 (基因名), Mitogen-activated protein kinase 7 (蛋白名), MK07_RAT.
产品名称:

Rat Mapk7/ Mitogen-activated protein kinase 7 ELISA Kit
丝裂原活化蛋白激酶7

货号:

E9212r

商标:
EIAab®
监管等级:
别名:

Big MAP kinase 1, Extracellular signal-regulated kinase 5, BMK-1, ERK-5, MAP kinase 7, Bmk1, Erk5

检测方法:
ELISA
特异性:
Natural and recombinant rat Mitogen-activated protein kinase 7
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cancer
Rat Mapk7 ELISA Kit
规格 & 价格: cart
×
Rat Mapk7 ELISA Kit
邮箱 *
消息 *
Please 登录.
产品说明书
在线询价


通用注释


亚单元:
Interacts with MAP2K5. Forms oligomers (By similarity). Interacts with MEF2A, MEF2C and MEF2D; the interaction phosphorylates the MEF2s and enhances transcriptional activity of MEF2A, MEF2C but not MEF2D. Interacts with SGK1 (By similarity). Interacts with PML (By similarity). Interacts (via N-terminal half) with HSP90AB1-CDC37 chaperone complex in resting cells; the interaction is MAP2K5-independent and prevents MAPK7 from ubiquitination and proteasomal degradation (PubMed:23428871).


功能:
Plays a role in various cellular processes such as proliferation, differentiation and cell survival. The upstream activator of MAPK7 is the MAPK kinase MAP2K5. Upon activation, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C. EGF activates MAPK7 through a Ras-independent and MAP2K5-dependent pathway. May have a role in muscle cell differentiation. May be important for endothelial function and maintenance of blood vessel integrity. MAP2K5 and MAPK7 interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. Phosphorylates SGK1 at Ser-78 and this is required for growth factor-induced cell cycle progression (By similarity). Involved in the regulation of p53/TP53 by disrupting the PML-MDM2 interaction.


亚细胞位置:
Cytoplasm Nucleus Nucleus PML body Translocates to the nucleus upon activation.


该产品尚未在任何出版物中被引用。
关闭
Sample Data
关闭
Sample Data
关闭
Sample Data
用户中心 close
购物车 close
我的收藏 close
我的足迹 close
清除
产品对比 close
用户中心
购物车
我的收藏
我的足迹
产品对比
回到顶部
通知
new 咨询
规格 数量 单价 (¥) 小计 1 (¥)
小计 2:
triangle
规格 数量 单价 (¥)
你想做我们的代理并得到更低的折扣吗?
请联系我们:
电话:027-59234612(+86)
传真:027-59234610(+86)
邮箱:sales@eiaab.com