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首页  >  酶联免疫试剂盒  >  Mouse Traf3ip1 ELISA Kit
Traf3ip1 (基因名), TRAF3-interacting protein 1 (蛋白名), MIPT3_MOUSE.
产品名称:

Mouse Traf3ip1/ TRAF3-interacting protein 1 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Intraflagellar transport protein 54 homolog, Microtubule-interacting protein associated with TRAF3, MIP-T3, Ift54, Mipt3

检测方法:
ELISA
特异性:
Natural and recombinant mouse TRAF3-interacting protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Immunology
Mouse Traf3ip1 ELISA Kit
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Mouse Traf3ip1 ELISA Kit
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产品说明书


通用注释


亚单元:
Interacts with IL13RA1. Binds to microtubules, TRAF3 and DISC1 (By similarity). Component of the IFT complex B, at least composed of IFT20, IFT22, HSPB11/IFT25, IFT27, IFT46, IFT52, TRAF3IP1/IFT54, IFT57, IFT74, IFT80, IFT81, and IFT88. Interacts with IFT88. Interacts with MAP4 (PubMed:26487268).


功能:
Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules (By similarity). Involved in epithelial morphogenesis and in the regulation of microtubule cytoskeleton organization. Is a negative regulator of microtubule stability, acting through the control of MAP4 levels (PubMed:26487268). Involved in ciliogenesis (PubMed:21945076).


亚细胞位置:
Cytoplasm Cytoskeleton Cell projection Cilium Cytoplasm Cytoskeleton Cilium axoneme Cytoplasm Cytoskeleton Cilium basal body Microtubules. In the cilium, it is observed at the ciliary base, ciliary transition zone and ciliary tip.


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