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首页  >  酶联免疫试剂盒  >  Bovine MIF ELISA Kit
MIF (基因名), Macrophage migration inhibitory factor (蛋白名), MIF_BOVIN.
产品名称:

Bovine MIF/ Macrophage migration inhibitory factor ELISA Kit
巨噬细胞迁移抑制因子

货号:

E0698b

商标:
EIAab®
监管等级:
别名:

MIF, L-dopachrome isomerase, L-dopachrome tautomerase, Phenylpyruvate tautomerase, p12A

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.625-40ng/ml
灵敏度:
0.312ng/ml
特异性:
Natural and recombinant bovine Macrophage migration inhibitory factor
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Immunology
Bovine MIF ELISA Kit
规格 & 价格: cart
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Bovine MIF ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS


通用注释


亚单元:
Homotrimer. Interacts with BNIPL (By similarity). Interacts with the CD74 extracellular domain. Interacts with COPS5 and with the CXCR2 extracellular domain.


功能:
Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.


亚细胞位置:
Secreted Cytoplasm Does not have a cleavable signal sequence and is secreted via a specialized, non-classical pathway. Secreted by macrophages upon stimulation by bacterial lipopolysaccharide (LPS), or by M.tuberculosis antigens (By similarity).



[1].
Biji Mathew, Jeffrey R Jacobson, Jessica H Siegler, Jaideep Moitra, Micheal Blasco, Lishi Xie, Crystal Unzueta, Tong Zhou, Carrie Evenoski...
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