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首页  >  酶联免疫试剂盒  >  Rat Mical2 ELISA Kit
Mical2 (基因名), [F-actin]-monooxygenase MICAL2 (蛋白名), MICA2_RAT.
产品名称:

Rat Mical2/ [F-actin]-monooxygenase MICAL2 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Molecule interacting with CasL protein 2, MICAL-2

检测方法:
ELISA
特异性:
Natural and recombinant rat [F-actin]-monooxygenase MICAL2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Rat Mical2 ELISA Kit
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Rat Mical2 ELISA Kit
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产品说明书


通用注释


亚单元:
Interacts with PLXNA4 (By similarity). Interacts with RAB1B (By similarity).


功能:
Nuclear monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin to form methionine-sulfoxide, resulting in actin filament disassembly and preventing repolymerization (By similarity). In the absence of actin, it also functions as a NADPH oxidase producing H(2)O(2) (By similarity). Acts as a key regulator of the SRF signaling pathway elicited by nerve growth factor and serum: mediates oxidation and subsequent depolymerization of nuclear actin, leading to increase MKL1/MRTF-A presence in the nucleus and promote SRF:MKL1/MRTF-A-dependent gene transcription. Does not activate SRF:MKL1/MRTF-A through RhoA (By similarity).


亚细胞位置:
Nucleus


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