027-59234612(+86)
EIAab
Home  >  ELISA Kit  >  Bovine MICAL2 ELISA Kit
MICAL2 (GeneName), [F-actin]-monooxygenase MICAL2 (ProteinName), MICA2_BOVIN.
Product Name:

Bovine MICAL2/ [F-actin]-monooxygenase MICAL2 ELISA Kit

Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

Molecule interacting with CasL protein 2, MICAL-2

Detection Method:
ELISA
Specificity:
Natural and recombinant bovine [F-actin]-monooxygenase MICAL2
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
Bovine MICAL2 ELISA Kit
Size & Price: Sign In.
×
Bovine MICAL2 ELISA Kit
Email *
Message *
Please Sign In.
Product Datasheets


General Annotation


Sub Unit:
Interacts with PLXNA4 (By similarity). Interacts with RAB1B (By similarity).


Function:
Nuclear monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin to form methionine-sulfoxide, resulting in actin filament disassembly and preventing repolymerization (By similarity). In the absence of actin, it also functions as a NADPH oxidase producing H(2)O(2) (By similarity). Acts as a key regulator of the SRF signaling pathway elicited by nerve growth factor and serum: mediates oxidation and subsequent depolymerization of nuclear actin, leading to increase MKL1/MRTF-A presence in the nucleus and promote SRF:MKL1/MRTF-A-dependent gene transcription. Does not activate SRF:MKL1/MRTF-A through RhoA (By similarity).


Subcellular Location:
Nucleus


This product has not yet been referenced specifically in any publications.

[1].
"MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion."

[2].
"Redox modification of nuclear actin by MICAL-2 regulates SRF signaling."

[3].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."

[4].
"Expression of novel molecules, MICAL2-PV (MICAL2 prostate cancer variants), increases with high Gleason score and prostate cancer progression."

[5].
"The MICAL proteins and rab1: a possible link to the cytoskeleton?"
Close
Sample Data
Close
Sample Data
Close
Sample Data
My Cart close
Attention close
History close
Clear All
Comparison close
User
My Cart
Attention
History
Comparison
Top
Message
close_message
Product Name *
Email *
Message: *
Inform
new Message
Size Quantity Price ($) Subtotal 1 ($)
Subtotal 2: $
triangle
Size Quantity Price ($)
Do you want to be our agent and get a lower discount?
Please contact us:
Tel:027-59234612(+86)
Fax:027-59759960(+86)
Email:sales@eiaab.com