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APOOL (基因名), MICOS complex subunit MIC27 (蛋白名), MIC27_HUMAN.
产品名称:

Human APOOL/ MICOS complex subunit MIC27 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Apolipoprotein O-like, Protein FAM121A, UNQ8193/PRO23204, CXorf33, FAM121A, MIC27

检测方法:
ELISA
特异性:
Natural and recombinant human MICOS complex subunit MIC27
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Human APOOL ELISA Kit
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Human APOOL ELISA Kit
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通用注释


亚单元:
Component of the mitochondrial contact site and cristae organizing system (MICOS) complex, composed of at least MINOS1/MIC10, CHCHD3/MIC19, CHCHD6/MIC25, APOOL/MIC27, IMMT/MIC60, APOO/MIC23/MIC26 and QIL1/MIC13. This complex was also known under the names MINOS or MitOS complex (PubMed:25764979, PubMed:25781180, PubMed:23704930, PubMed:25764979, PubMed:25781180, PubMed:25997101). The MICOS complex associates with mitochondrial outer membrane proteins SAMM50, MTX1, MTX2 and DNAJC11, mitochondrial inner membrane protein TMEM11 and with HSPA9. Interacts with MINOS1/MIC10, IMMT/MIC60 and APOO/MIC23/MIC26 (PubMed:25764979, PubMed:25781180, PubMed:23704930, PubMed:25764979, PubMed:25781180, PubMed:25997101).


功能:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function (PubMed:23704930), (PubMed:25764979).


亚细胞位置:
Mitochondrion inner membrane Multi-pass membrane protein Mitochondrion


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