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首页  >  酶联免疫试剂盒  >  Bovine APOO ELISA Kit
APOO (基因名), MICOS complex subunit MIC26 (蛋白名), MIC26_BOVIN.
产品名称:

Bovine APOO/ MICOS complex subunit MIC26 ELISA Kit
MICOS复合体亚基

货号:

E10480b

商标:
EIAab®
监管等级:
别名:

Apolipoprotein O, MICOS complex subunit MIC23, Protein FAM121B, FAM121B, MIC23, MIC26

检测方法:
ELISA
特异性:
Natural and recombinant bovine MICOS complex subunit MIC26
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Bovine APOO ELISA Kit
规格 & 价格: cart
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Bovine APOO ELISA Kit
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产品说明书


通用注释


亚单元:
Component of the mitochondrial contact site and cristae organizing system (MICOS) complex, composed of at least MINOS1/MIC10, CHCHD3/MIC19, CHCHD6/MIC25, APOOL/MIC27, IMMT/MIC60, APOO/MIC23/MIC26 and QIL1/MIC13. This complex was also known under the names MINOS or MitOS complex. The MICOS complex associates with mitochondrial outer membrane proteins SAMM50, MTX1, MTX2 and DNAJC11, mitochondrial inner membrane protein TMEM11 and with HSPA9. Interacts with IMMT/MIC60. Interacts with MINOS1/MIC10 and APOOL/MIC27.


功能:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a crucial role in crista junction formation and mitochondrial function. Can induce cardiac lipotoxicity by enhancing mitochondrial respiration and fatty acid metabolism in cardiac myoblasts. Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP)-dependent mechanism, probably as a VLDL-associated protein that is subsequently transferred to HDL.


亚细胞位置:
Mitochondrion inner membrane Single-pass membrane protein Secreted Mitochondrion Endoplasmic reticulum membrane Golgi apparatus membrane Exists in three distinct forms: a glycosylated and secreted form, an ER/Golgi-resident form and a non-glycosylated mitochondrial form.


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