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CHCHD6 (GeneName), MICOS complex subunit MIC25 (ProteinName), MIC25_BOVIN.
Product Name:

Bovine CHCHD6/ MICOS complex subunit MIC25 ELISA Kit

Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

Coiled-coil-helix-coiled-coil-helix domain-containing protein 6, MIC25

Detection Method:
ELISA
Specificity:
Natural and recombinant bovine MICOS complex subunit MIC25
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
Bovine CHCHD6 ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
Component of the mitochondrial contact site and cristae organizing system (MICOS) complex, composed of at least MINOS1/MIC10, CHCHD3/MIC19, CHCHD6/MIC25, APOOL/MIC27, IMMT/MIC60, APOO/MIC23/MIC26 and QIL1/MIC13. This complex was also known under the names MINOS or MitOS complex. The MICOS complex associates with mitochondrial outer membrane proteins SAMM50, MTX1, MTX2 and DNAJC11, mitochondrial inner membrane protein TMEM11 and with HSPA9. Interacts with DISC1. Interacts with IMMT/MIC60.


Function:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.


Subcellular Location:
Mitochondrion inner membrane Lipid-anchor Mitochondrion


This product has not yet been referenced specifically in any publications.

[1].
"CHCM1/CHCHD6, novel mitochondrial protein linked to regulation of mitofilin and mitochondrial cristae morphology."

[2].
"The mitochondrial inner membrane protein mitofilin exists as a complex with SAM50, metaxins 1 and 2, coiled-coil-helix coiled-coil-helix domain-containing protein 3 and 6 and DnaJC11."

[3].
"Detailed analysis of the human mitochondrial contact site complex indicate a hierarchy of subunits."

[4].
"QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology."

[5].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."
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