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Chchd3 (基因名), MICOS complex subunit Mic19 (蛋白名), MIC19_MOUSE.
产品名称:

Mouse Chchd3/ MICOS complex subunit Mic19 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Coiled-coil-helix-coiled-coil-helix domain-containing protein 3, Mic19

检测方法:
ELISA
特异性:
Natural and recombinant mouse MICOS complex subunit Mic19
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Mouse Chchd3 ELISA Kit
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Mouse Chchd3 ELISA Kit
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通用注释


亚单元:
Component of the mitochondrial contact site and cristae organizing system (MICOS) complex, composed of at least MINOS1/MIC10, CHCHD3/MIC19, CHCHD6/MIC25, APOOL/MIC27, IMMT/MIC60, APOO/MIC23/MIC26 and QIL1/MIC13. This complex was also known under the names MINOS or MitOS complex. The MICOS complex associates with mitochondrial outer membrane proteins SAMM50, MTX1, MTX2 and DNAJC11, mitochondrial inner membrane protein TMEM11 and with HSPA9 (By similarity). Found in a complex with IMMT/MIC60 and SAMM50 termed mitochondrial intermembrane space bridging (MIB) complex. Interacts with IMMT/MIC60 (By similarity). Interacts with HSPA1A/HSPA1B and OPA1, preferentially with the soluble OPA1 form.


功能:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology.


亚细胞位置:
Mitochondrion inner membrane Lipid-anchor Intermembrane side Cytoplasm Nucleus Mitochondrion


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