本公司产品仅供科研使用,不用于人体及临床诊断。
027-59234612(+86)
我的积分
注册  /  登录
EIAab
首页  >  酶联免疫试剂盒  >  Mouse Mib1 ELISA Kit
Mib1 (基因名), E3 ubiquitin-protein ligase MIB1 (蛋白名), MIB1_MOUSE.
产品名称:

Mouse Mib1/ E3 ubiquitin-protein ligase MIB1 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

DAPK-interacting protein 1, DIP-1, Mind bomb homolog 1, RING-type E3 ubiquitin transferase MIB1, Dip1, Kiaa1323, Mib

检测方法:
ELISA
特异性:
Natural and recombinant mouse E3 ubiquitin-protein ligase MIB1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Development Biology
Mouse Mib1 ELISA Kit
×
Mouse Mib1 ELISA Kit
邮箱 *
消息 *
Please 登录.
产品说明书


通用注释


亚单元:
Interacts with CEP131 and PCM1.


功能:
E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. Involved in ubiquitination of centriolar satellite CEP131, CEP290 and PCM1 proteins and hence inhibits primary cilium formation in proliferating cells. Mediates 'Lys-63'-linked polyubiquitination of TBK1, which probably participates in kinase activation (By similarity). Probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.


亚细胞位置:
Cytoplasm Cytoskeleton Microtubule organizing center Centrosome Centriolar satellite Cytoplasm Cell membrane Displaced from centriolar satellites in response to cellular stress, such as ultraviolet light (UV) radiation or heat shock (By similarity). Localizes to the plasma membrane.


该产品尚未在任何出版物中被引用。
关闭
Sample Data
关闭
Sample Data
关闭
Sample Data
用户中心 close
购物车 close
我的收藏 close
我的足迹 close
清除
产品对比 close
用户中心
购物车
我的收藏
我的足迹
产品对比
回到顶部
消息
close_message
产品名称 *
邮箱 *
消息 *
通知
new 留 言
规格 数量 单价 (¥) 小计 1 (¥)
小计 2:
triangle
规格 数量 单价 (¥)
你想做我们的代理并得到更低的折扣吗?
请联系我们:
电话:027-59234612(+86)
传真:027-59234610(+86)
邮箱:sales@eiaab.com